Synonyms:
Natamycin
S1517-50MG
S1517-200MG
S1517-100MG
101760-840EA
120
USD
InStock
101760-840
101760-842
101760-838
Pimamicin ~99%
Pimaricin
Pimaricin ( synonym Natamycin), a natural and versatile anti-fungal agent during fermentation by the bacterium Streptomyces natalensis, commonly found in soil, with little to no flavour interference.
- DMSO Solubility of 7 mg/mL (10.51 mM)
Natamycin binds specifically to ergosterol present in model membranes. Natamycin does not change the permeability of the yeast plasma membrane under conditions that growth is blocked. Natamycin perturbs the cellular vacuole morphology, causing the formation of many more small vacuolar structures in yeast cells. Natamycin inhibits the priming stage of vacuole fusion. Natamycin shows low MIC against the dematiaceous fungi, Curvularia species.