Synonyms:
Polyethylene glycol diacrylate
, Poly(ethylene glycol) diacrylate
, PEG bisacrylate
, PEG hydrogel
, PEGDA
, PEG diacrylate
GS755-2EA
103792-972PK
209.23
USD
InStock
103792-972
PEGSSDA
Polyethylene glycol diacrylate (PEGDA)
A Thiol-reactive crosslinker that allows for easy dissolution of HyStem
- Use PEGSSDA to allow the non-enzymatic digestion of HyStem hydrogels
PEGSSDA allows researchers to quickly and gently dissolve HyStem® hydrogels non-enzymatically and easily recover cells grown on top or within the hydrogel. PEGSSDA contains two internal disulfide bonds which are rapidly reduced with small amounts of reducing agent causing gel liquefaction.
PEGSSDA allows researchers to quickly and gently dissolve HyStem® hydrogels non-enzymatically, thereby easily recovering cells or spheroids either grown on top or within the hydrogel. PEGSSDA contains two internal disulfide bonds which are rapidly reduced with small amounts of reducing agent (such as N-acetyl cysteine or glutathione), causing gel liquefaction.
PEGSSDA is a pentablock PEGDA molecule composed of four PEG molecules (MW 2000 Da) and two interdigitated disulfide bonds. Only the external PEG molecules are acrylated. The final molecular weight is approximately 8500 Da. Like PEGDA, PEGSSDA is a thiol-reactive crosslinker that covalently reacts with the thiol groups in Glycosil®, HyStem, Heprasil®, and Gelin-S® to form viscoelastic hydrogels. PEGSSDA is lyophilized in water.
Caution: This product is for R&D use only and is not intended for human or other uses. Please consult the Material Safety Data Sheet for information regarding hazards and safe handling practices.