Synonyms:
TPEN
, N1,N1,N2,N2-Tetrakis(pyridin-2-ylmethyl)ethane-1,2-diamine
, Tetrakis-(2-pyridylmethyl)ethylenediamine
450-011-M100
89151-394EA
98.1
USD
InStock
89151-394
N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine ≥97% (by non aqueous titration)
N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine
Heavy metal chelator.
A cell permeable and extremely high-affinity chelator of heavy metals, yet with low affinity for Mg²⁺ and Ca²⁺.
Lipid-soluble, crossing both natural and artificial membranes. TPEN can be used in conjunction with QUIN 2 or QUIN 2/AM to reduce heavy-metal quenching of QUIN 2 fluorescence in cells. Ion specificity is Zn²⁺>Fe²⁺>Mn²⁺>>Ca²⁺=Mg²⁺. Complex with Fe²⁺ catalyses superoxide dismutation.
Soluble in dimethyl formamide, DMSO, 100% ethanol or methanol.