Synonyms:
SYM 2081
550-186-M005
89152-296EA
100.61
USD
InStock
89152-296
(2S,4R)-4-Methylglutamic acid ≥97%
(2S,4R)-4-Methylglutamic acid
Potent and highly selective kainate receptor agonist, with an IC50 for inhibition of [3H]-kainate binding of 35 nM and almost 3,000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. Also selectively inhibits the cloned excitatory amino acid transporter EAAT2 at higher concentrations.
White powder.
Soluble in dilute aqueous acid.