Synonyms:
Lipopolysaccharide
581-014-L002
89152-776EA
275.88
USD
InStock
89152-776
Lipopolysaccharides (from E.coli) serotype J5 (Rc), TLRgrade™ ready-to-use
Lipopolysaccharides
TLR4 activator.
Rough (R)-form LPS isolated and purified from E. coli J5 (Rc mutant) by a modification of the PCP extraction method, converted to the uniform sodium salt form and dissolved in sterile pyrogen-free double distilled water.
Strong activator of Toll-like receptor 4 (TLR4). Does not activate TLR2 or other TLRs as determined with splenocytes and macrophages from TLR4 deficient mice. No further re-extraction required. Smooth (S)-form LPS are commonly the preferred choice for whole animal studies, whereas Rough (R)-form LPS are primarily used in cellular in vitro activation studies.