Synonyms:
Lipopolysaccharide
581-017-L002
89152-780EA
277.54
USD
InStock
89152-780
Lipopolysaccharides (from Salmonella minnesota), TLRgrade™
Lipopolysaccharides
TLR4 activator.
Rough (R)-form LPS isolated and purified from Salmonella minnesota R5 (Rc mutant) by a modification of the PCP extraction method, converted to the uniform sodium salt form.
Strong activator of Toll-like receptor 4 (TLR4). Does not activate TLR2 or other TLRs as determined with splenocytes and macrophages from TLR4 deficient mice. No further re-extraction required. Smooth (S)-form LPS are commonly the preferred choice for whole animal studies, whereas Rough (R)-form LPS are primarily used in cellular in vitro activation studies.