Synonyms:
Monophosphoryl Lipid A
581-203-R500
581-203-L001
76002-222EA
365.34
USD
InStock
76002-222
89152-796
MPLA (from E.coli) ≥99.9% serotype R515 (Re), TLRgrade™ ready-to-use
MPLA
TLR4 activator.
Isolated from E. coli, Serotype R515 (Re mutant). Prepared by acid hydrolysis from purified E. coli, Serotype R515 (Re) LPS (isolated by a modification of the PCP extraction method), converted to the uniform salt form.
Activates TLR4 (Toll-like receptor 4). Does not activate TLR2 as determined with splenocytes and macrophages from TLR4 deficient mice. Exhibits reduced endotoxic and pyrogenic activity compared to lipid A and LPS.
Synonym: MPL-A from E. coli, Serotype R515 (Re).