Synonyms:
3-[(3-chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione
, 3-((3-Chloro-4-hydroxyphenyl)amino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione
BML-EI311-0005
BML-EI311-0001
89158-042EA
289.77
USD
InStock
89158-042
89158-040
SB-415286 ≥98% (by HPLC)
SB-415286
Potent and selective inhibitor of GSK-3β (IC50=78nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke.
Yellow Solid.
Soluble in DMSO, ethanol or methanol.