Synonyms:
AMPK Signaling Activator VII
, Metformin
, 1,1-Dimethylbiguanide Hydrochloride
, Metformin hydrochloride
317240-5GM
317240-5GM
80016-622EA
225.3
USD
InStock
CA80016-622
80016-622
1,1-Dimethylbiguanide hydrochloride, Sigma-Aldrich®
1,1-Dimethylbiguanide hydrochloride
An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia. Reported to stimulate AMP-activated protein kinase (AMPK) leading to the reduction in acetyl-CoA carboxylase (ACC) activity and induction of fatty acid oxidation.