Synonyms:
Sulphosuccinimidyl-3 -(4-hydroxypheynyl) propionate
, sulfosuccinimidyl-3 -(4-hydroxypheynyl) propionate
, Water-Soluble Bolton-Hunter Reagent
, 3-(4-Hydroxy-phenyl)-propionic acid-OSu
27712
27712
PI27712EA
814.15
USD
InStock
PI27712
CAPI27712
Bolton-Hunter reagent (Sulfo-SHPP), Pierce™
Bolton-Hunter reagent (Sulfo-SHPP)
Sulfo-SHPP, sulfosuccinimidyl-3 -(4-hydroxypheynyl) propionate, also known as water-soluble Bolton-Hunter reagent, conjugates tyrosine-like functional groups to primary amines to increase the number of tyrosyl groups that can be iodinated by iodine-125 labeling procedures.
- Iodinate before or after coupling to the molecule of interest
- Preserves tyrosine residues that are essential for protein function or immunogenicity
- NHS esters react efficiently with primary amino groups in pH 7 to 9 buffers to form stable amide bonds
Sulfo-SHPP is useful for introducing tyrosyl groups on proteins sensitive to small amounts of organic solvent and for labelling cell surfaces without exposing the cells to membrane permeable solvents.
Caution: For Research Use Only. Not for use in diagnostic procedures.