Synonyms:
Enhanced JC-1
CDX-T0103-M001
CDX-T0103-M005
102981-250EA
139.85
USD
InStock
102981-250
102981-252
JC-10 ≥98% (by HPLC)
JC-10
Derivative of JC-1 useful for determining mitochondrial membrane potential by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. Accumulates in mitochondria, selectively generating an orange J-aggregate emission profile (570 nm) in healthy cells. Upon cell injury, as membrane potential decreases, JC-10 monomers are generated, resulting in a shift to green emission (520 nm). Shows improved solubility compared to JC-1 in aqueous media and an ability to detect subtler changes in mitochondrial membrane potential loss. Spectral data: lambdaex 510 nm| lambdaem 525.