Synonyms:
3-[6-Amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenol
AB287004-5MG
AB287004-25MG
76317-878EA
206.84
USD
InStock
76317-878
76317-876
K02288 ≥98% (by HPLC)
K02288
A potent and selective inhibitor of type I bone morphogenic protein (BMP) receptors (IC₅₀ values are 1.1, 1.8, 6.4, 34.4, 220, 302 and 321 nM for ALK2, ALK1, ALK6, ALK3, ActRIIA, ALK4 and ALK5 respectively). K02288 can prevent BMP4-induced SMAD1/5/8 pathway activation in vitro (IC₅₀ = 100 nM) without affecting TGF-β signaling.
- Type I bone morphogenic protein (BMP) receptors inhibitors