Synonyms:
DiSC2(5)
, 3-Ethyl-2-[5-(3-ethyl-2(3H)-benzothiazolylidene)-1,3-pentadienyl]benzothiazolium iodide
, DTDCI
40041
89139-114EA
90.48
USD
InStock
89139-114
3,3'-Diethylthiadicarbocyanine iodide [DiSC₂(5)] ≥95% (by TLC) DNA/RNA binding dye
3,3'-Diethylthiadicarbocyanine iodide [DiSC₂(5)]
DiSC2(5) (3,3′-Diethylthiadicarbocyanine, iodide) binds to DNA-DNA or PNA-DNA duplexes with a large blue-shift of the absorption spectrum. Binding of the dye to PNA-DNA hybrid, in particular, blue-shifts the dye absorption spectrum by as much as 115 nm, offering a visual method to detect nucleic acid hybridization.
- λAbs (pH 7.5 buffer) = 646 nm (free dye); ~586 nm (dsDNA); ~531 nm (PNA-DNA)
- Dark solid soluble in DMSO or MeOH
- Store at 4°C