Synonyms:
3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate
, 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulphonate
, CHAPS
0219031925
0219031905
0219031901
0219031980
IC19031925EA
1251.82
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InStock
IC19031925
IC0219031980
IC19031905
IC19031901
3-[(3-Cholamidopropyl)dimethylammonio]-1-propane sulfate (CHAPS) ≥98%, white powder
3-[(3-Cholamidopropyl)dimethylammonio]-1-propane sulphate (CHAPS)
CHAPS is a nondenaturing zwitterionic detergent for solubilizing membrane proteins and breaking protein-protein interactions. Combines the useful properties of both the sulfobetaine-type and the bile salt detergents.
- pH: 4.0 - 7.0 (10% aq soln)
- Aggregation Number: 4-14 (0-0.1 M Na+)
- Critical Micelle Concentration (CMC): 6-10 mM
CHAPS is commonly used for protein solubilization in isoelectric focusing and two-dimensional electrophoresis especially for non-denaturing (without urea) isoelectric focusing. CHAPS has been shown to give excellent resolution of some subcellular preparations and plant proteins. Its small micellar molecular weight (6150) and high CMC (6-10 mM) allow it to be removed from samples by dialysis. Can be used as a non-toxic stabilizing agent for growth factors.
Soluble in water (100 mg/ml - clear, colorless to slightly yellow solution).
Caution: Research Use Only (RUO).