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Guide to Selecting Tubing for Pumps and Fluid Handling Systems

The right pump tubing is crucial when building your fluid processing pump system. Before you choose, consider all aspects of your application: chemical compatibility, operating temperature, pressure, necessary regulatory approvals, gas permeability of the tubing, and cleaning/sterilization requirements.

Use the "Tubing Selection Guide" below to help you select the appropriate tubing for your application. The Chemical Compatibility guide and the chemical resistance summary in the table below are only guidelines. Chemical resistance and tubing wear may vary according to use always test the tubing you select under the actual conditions.

We are here to help you determine just the right tubing for your pump and fluid handling needs. Learn more about chemical classifications and formulations below.

Chemical Resistance Classifications

A —No damage after 30 days of constant exposure.
B —Little or no damage after 30 days of constant exposure.
C —Some effect after 7 days of constant exposure. Effects may include: cracking, crazing, loss of strength, discoloration, softening, or swelling. Softening and swelling are reversible in some cases.
D —Not recommended for continuous use. Immediate damage may occur.
"_" —Test data unavailable or not applicable.

Formulation Operating
temperature
Resin
certification(s)
Durometer Chemical resistance summary Permeability (approx)†
Units: {cc-mmsec-cm2-cm Hg } x 10-10
Acids,
weak
Acids,
strong
Bases,
weak
Bases,
strong
Ozone UV
light
CO2 H2 O2 N2
Bev-A-Line® IV -60 to 160°F
(-51 to 71°C)
FDA, USP, USDA, 80 (D) B D B B D — — — — —
Bev-A-Line® V -60 to 200°F
(-51 to 93°C)*
National Formulary 80 (D) B B B B D — — — — —
Bev-A-Line® XX -60 to 160°F
(-51 to 71°C)
FDA*, NSF* 55 (D) C D C D C A — — — —
C-FLEX® -100 to 275°F
(-73 to 135°C)
FDA, USP, USDA, GMP 50 (A) A A A A — B — — 150 —
Chemfluor® 367 -400 to 450°F
(-240 to 260°C)
FDA 58 (A) A A A A A — — — — —
Copper -60 to 400°F
(-53 to 204°C)
None — D D C C A A — — — —
EPDM food-grade;
PTFE-lined;
wire-reinforced
-40 to 300°F
(-40 to 148°C)
FDA, USDA, 3A — A B A A — — — — — —
ETFE -150 to 302°F
(-101 to 150°C)
GMP 75 (D) A A A A A A — — — —
FEP -454 to 400°F
(-270 to 205°C)
FDA, USP, GMP 55 (D) A A A A A A 5.9 1.3 14 2.0
Gum rubber -15 to 158°F
(-26 to 70°C)
GMP 35 (A) A D A B C D 1311 492 307 118
Hypalon® 40 to 220°F
(4 to 104°C)
None 70 (D) — A — — — — — — — —
Kynar® -40 to 260°F
(-40 to 127°C)
FDA, USP, USDA 80 (D) A A A A A A — — — —
MFA -103 to 482°F
(-75 to 250°C)
USP 59 (D) A A A A A A — — — —
Norprene® -75 to 275°F
(-60 to 135°C)
GMP 61 (A) A B A C A B 1200 — 80 200
Norprene® food-grade -60 to 275°F
(-51 to 135°C)
FDA, NSF, GMP 61 (A) A B A C A B 1200 — 80 200
Norprene® pressure -60 to 275°F
(-51 to 135°C)
FDA, 3A, NSF 61 (A) A B A C A B 1200 — 80 200
Nylon -60 to 200°F
(-51 to 93°C)
None — A D A C C D 20 19 5.4 1.1
PEEK Up to 212°F
(Up to 100°C)
None — A A A A A A — — — —
PFA -320 to 500°F
(-195 to 260°C)
FDA, USP, GMP 60 (D) A A A A A A — — — —
PFA-450 high-purity -320 to 500°F
(-195 to 260°C)
FDA, GMP 60 (D) A A A A A A — — — —
PharMed® -75 to 275°F
(-59 to 135°C)
FDA, USP, NSF, GMP 64 (A) A B A C A B 1200 — 80 200
Polyethylene -100 to 175°F
(-73 to 80°C)
FDA, USDA 50 (D) A D B B B A 280 — 60 20
Polyethylene,
FEP-lined
-100 to 175°F
(-73 to 80°C)
FDA, GMP — A A A A A A 5.9* 1.3* 14* 2.0*
Polyimide -418 to 896°F
(-250 to 480°C)
USP, NEMA — A A A A A A — — — —
Polypropylene 32 to 250°F
(0 to 121°C)
FDA, USDA 75 (D) A D B B C D 90 — 25 4
Polyurethane
(clear, aqua-tint)
-40 to 180°F
(-40 to 82°C)
None 95 (A) B D B B A — 395 66 10.5 17.1
Polyurethane
(red, green,
blue, black)
-70 to 185°F
(-57 to 85°C)
None 95 (A) B D B B A — 395 66 10.5 17.1
PTFE -400 to 500°F
(-240 to 260°C)
FDA, USP, GMP 50 (D) A A A A A A 6.8 — — 1.0
PTFE
color-coded
-400 to 500°F
(-240 to 260°C)
None 50 (D) A A A A A A 6.8 — — 1.0
PVC 10 to 140°F
(-12 to 60°C)
None 65 (A) A A A A A A 6.8 — — 1.0
PVC Bubble® -5 to 180°F
(-21 to 82°C)
None 55 (A) A D A D B D 1305 — 1345 —
PVC food-grade 10 to 140°F
(-12 to 60°C)
FDA, 3A, USDA 65 (A) A A A A A A 6.8 — — 1.0
PVC reinforced -5 to 180°F
(-21 to 82°C)
FDA, USDA, NSF, 3A 65 (A) A D A A B D 36 — 36 —
PVC
wire-reinforced
25 to 150°F
(-4 to 65°C)
FDA, USDA, 3A, NSF 70 (A) A D A A B D 36 — 36 —
Silicone,
peroxide-cured
-60 to 460°F
(-51 to 238°C)
FDA, USP, GMP 50 (A) B D A A A — 20,132 6579 7961 2763
Silicone,
platinum-cured
-60 to 460°F
(-51 to 238°C)
FDA, USP, USDA, GMP 50 (A) B D A A A — 20,132 6579 7961 2763
Silicone
reinforced,
peroxide
-60 to 400°F
(-51 to 204°C)
FDA, USP, GMP 60 (A) B D A A A — 20,132 6579 7961 2763
Stainless steel, 316 -65 to 550°F
(-53 to 289°C)
None — A B A C A A — — — —
Tygon®,
FEP-lined
-40 to 180°F
(-40 to 82°C)
FDA*, USP*, GMP 67 (A) A A A A B B 5.9* 1.3* 14* 2.0*
Tygon®
fuel/lubricant
-35 to 165°F
(-37 to 74°C)
GMP 57 (A) B C C D A A 100 — 12 22
Tygon®
food/beverage
-49 to 165°F
(-45 to 74°C)
FDA, NSF, 3A 63 (A) A B A B B D 270 — 30 60
Tygon®
high-purity
-94 to 125°F
(-70 to 52°C)
FDA, USP, GMP 72 (A) A C A A B B 745 — 135 45
Tygon®
high-purity reinforced
-94 to 125°F
(-70 to 52°C)
FDA, NSF, GMP 72 (A) A C A A B B 745 — 135 45
Tygon®
lab; vacuum
-58 to 165°F
(-50 to 74°C)
FDA, GMP 55 (A) A D A D B D 360 — 40 80
Tygon®
LFL
-58 to 165°F
(-50 to 74°C)
FDA, USP, GMP 56 (A) A A A B — — — — — —
Tygon®
pressure
-47 to 165°F
(-44 to 74°C)
FDA, 3A, NSF 65 (A) A A B A — — 2700 — 600 300
Tygon®
sanitary
silicone pres.
-112 to 320°F
(-51 to 160°C)
FDA, USP, NSF, GMP 70 (A) B D A A A — — — — —
Tygon®
silicone
-112 to 392°F
(-80 to 200°C)
FDA, USP, NSF, GMP 50 (A) A C A A B B — — — —
Tygon®
ultra
chemical-resistant
-108 to 125°F
(-78 to 52°C)
GMP 72 (A) A C A A B B 4840 — 980 350
Tygothane®
pressure
-100 to 180°F
(-73 to 82°C)
FDA, NSF 82 (A) C C B D A — 1680 — 180 60
Vinyl -45 to 180°F
(-43 to 82°C)
GMP 67 (A) A D A A C D 360 — 40 80
Viton® -25 to 400°F
(-32 to 204°C)
GMP 75 (A) A A C D A A 79 — 15 4.3

*Based on liner
†At 25°C
Bev-A-Line—Reg TM Thermoplastic Processes, Inc.
Bubble—Reg TM Sherwood Medical Industries Inc.
Chemfluor, Norprene, PharMed, Tygon, Tygothane—Reg TM Norton Performance Plastics Corp.
C-FLEX—Reg TM Consolidated Polymer Technologies, Inc.
Hypalon, Viton—Reg TM DuPont Dow Elastomers L.L.C.
Kynar, Superflex—Reg TM Elf Atochem North America

Pump tubing for a wide range of applications and markets

Pump tubing is used for a variety of applications and in a wide range of markets and industries such as:

  • Life Science Research Solutions, Products, and Resources
  • Chromatography and Mass Spectrometry
  • Analytical Chemistry
  • Biopharma Production
  • Safety
  • Controlled Environment and Cleanroom Solutions

All have trusted Masterflex® pump tubing for their specific needs. Visit our website or contact us for further information.

The tubing guide you need

Need more guidance on selecting peristaltic pump tubing? Our Masterflex® pump tubing selection guides can help: Learn more about matching peristaltic pump tubing to the fluid you plan to use.

We’re here to help you keep your research going. Contact us with any questions you have about pump tubing.