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SELLECK CHEMICALS LLC MS
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SELLECK CHEMICALS LLC MS
Supplier:
Selleck Chemicals
Description:
Tacrolimus is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin creating a new ...
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Selleck Chemicals
Description:
HPI-4 (Ciliobrevin A) is a hedgehog (Hh) pathway antagonist. It blocks Sonic hedgehog (Shh)-induced Hh pathway activation (IC50 = 7 μM) downstream of ...
Catalog Number:
(101759-612)
Supplier:
Selleck Chemicals
Description:
Imiquimod is a novel synthetic agent with immune response modifying activity.
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Selleck Chemicals
Description:
Plerixafor (AMD3100) is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, re...
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Selleck Chemicals
Description:
Nebivolol HCl selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM.
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Selleck Chemicals
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MLN9708 gets hydrolyzed to its biologically active form MLN2238, on exposure to aqueous solutions or plasma
Supplier:
Selleck Chemicals
Description:
PD0325901 (PD325901) is selective and non ATP-competitive MEK inhibitor with an IC50 of 0.33 nM, roughly 500-fold more potent than CI-1040 on the phos...
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Selleck Chemicals
Description:
MG-132 is a potent cell-permeable inhibitor of proteasome and calpain with an IC50 of 100 nM.
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Selleck Chemicals
Description:
Trametinib is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of...
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Selleck Chemicals
Description:
Y-27632 2HCl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM in a cell-free assay, exhibits >200-fold selectivity over othe...
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Selleck Chemicals
Description:
Ciclesonide is a glucocorticoid used to treat obstructive airway diseases.
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Selleck Chemicals
Description:
Clofarabine inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.
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Selleck Chemicals
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Posaconazole is an inhibitor primarily of CYP3A4, but it does not inhibit the activity of other CYP enzymes; Also an inhibitor of sterol C14ɑ demethyl...
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Selleck Chemicals
Description:
Tofacitinib citrate (CP-690550 citrate) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively.
Supplier:
Selleck Chemicals
Description:
β-Sitosterol is one of several phytosterols (plant sterols) with chemical structures similar to that of cholesterol.
Supplier:
Selleck Chemicals
Description:
CB1954(Tretazicar) is a anticancer prodrug that is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a ...
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