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Monarch® Nucleic Acid Purification

Monarch® Nucleic Acid Purification

Monarch® Nucleic Acid Purification Kits are the perfect complement to many molecular biology workflows. Recover pure, intact DNA and RNA in minutes with our fast, user-friendly protocols and optimized buffer systems, and focus your time on the experiments that will drive your research forward. The Monarch nucleic acid purification portfolio can serve your needs, whether you are isolating nucleic acids from biological samples, cleaning up DNA and RNA from enzymatic reactions, extracting DNA fragments from gels, or purifying plasmids. 


Monarch kits are all designed with sustainability in mind; whenever possible, kits and components are made with significantly less plastic and are packaged with responsibly-sourced, recyclable packaging. Furthermore, plastic recovered during the manufacture of Monarch columns is used to manufacture other plastic-based NEB products. 

Product selection

Monarch Plasmid Miniprep Kit

Rapidly and reliably purify high quality plasmids from bacteria. Benefit from colored buffers, low elution volumes, and enjoy a sustainable design.

Monarch DNA Gel Extraction Kit

Extract and purify high quality DNA from agarose gels with excellent yields. Use elution volumes as low as 6 µl for highly concentrated DNA.

Monarch PCR & DNA Cleanup Kit (5 µg)

Rapidly purify high-quality DNA fragments from PCR and other enzymatic reactions. This kit can also be used for purification of oligonucleotides.

Monarch Total RNA Miniprep Kit

Purify total RNA > 20 nts from cells, tissues, blood and other samples using one convenient kit. Dnase I, Proteinase K and stabilization reagent included.

Monarch RNA Cleanup Kits

Quickly clean up & concentrate RNA after IVT, enzymatic treatment, and extraction. Available in 3 different binding capacities: 10, 50, and 500 μg.

Monarch HMW DNA Extraction Kits

Extract HMW DNA rapidly < 90 min using a novel glass bead-based method. Achieve DNA in Mb range for long read sequencing.

Monarch Genomic DNA Extraction Kits

Purify genomic DNA using silica-based method. Generate high DNA purity & yields from even challenging tissues for downstream qPCR, NGS, sequencing.